Endocrine Abstracts

Background: The association between Graves’ disease and thymic hyperplasia is well documented in the literature. Despite that it remains largely unrecognized in routine clinical practice. The lack of familiarity of usually benign nature of thymic hyperplasia associated with Graves’ disease may result in an aggressive management course, along with associated risks.Case presentation: A previously healthy 32-year-old female was admitted to hospita...

Acute and chronic alcohol intake and alcohol withdrawal induce dysfunction of neuroendocrine and other regulatory systems. The aims of this study were to assess a possible hypothalamo-pituitary-adrenal (HPA) axis dysfunction in population of alcoholics, using dexamethasone suppression test (DST). The study was approved by local Ethical Committee. The serum and urinary cortisol were compared between the groups of 89 male patients (64.5% depressive and 35.5% nondepressive alcoho...

Objective: To analyse the semen quality in patients with newly diagnosed non-Hodgkin lymphoma before starting the treatment.Materials and methods: We evaluated semen quality in 29 patients with non-Hodgkin lymphoma who underwent sperm banking in our clinic over a 9-year period. Semen samples were collected by masturbation after 2–7 days of sexual abstinence. Age at banking, semen volume, sperm concentration, and total and progressive sperm motility ...

In the recent years, knowledge about cancer biomarkers has increased tremendously providing great opportunities for improving the diagnosis, prognosis and treatment of cancer patients. In clinical practice, the levels of serum calcitonin, and carcinoembryonic antigen (CEA) are important during follow-up for patients with medullary thyroid cancer (MTC). Carbohydrate antigen 19-9 (CA 19-9), routinely used in the monitoring of pancreatic, hepatobiliary, and colon carcinoma, also ...

In order to compare effects of treatment in hyperthyroid patients treated with thyrostatic drug alone and those treated with thyrostatic plus levothyroxine we reviewed data from 60 consecutive patients attending our outpatient clinic. 27 patients, 25 ♀ and 2 ♂, aged 27–68 years were treated with thyrostatic drug alone, while 33 patients, 31 ♀ and 2 ♂, aged 19–88 years received thyrostatic plus levothyroxine. Number of remissions was greate...

We retrospectively collected data from 62 pregnant females who were followed for hyperthyroidism (n=17), hypothyroidism (n=21), euthyroid Hashimoto’s thyroiditis (n=9), and simple goitre and other non-autoimmune thyroid diseases (n=15).Among them 33 showed at least once during pregnancy low FT4, or low FT3 and FT4 in total on 74 occasions. Low FT4 was found on 15, low FT3 on 15 and low FT<s...

Last 10 years, we are living in iodine sufficient environment. To clarify natural course of thyroid autonomy in this conditions, we investigated 100 consecutive patients in last three months – 93 female and 7 male aged 19–86 years. Included were patients with scans showing thyroid autonomy, and patients with nodular or diffuse goiter with low or suppressed TSH. We followed them from their first visit. Thirty patients were hyperthyroid – one spontaneously cured, ...